Child Health and Education Lab
Allison King, MD, MPH, PhD
Allison King, MD, PhD, directs the Child Health and Education Laboratory, which focuses on children with chronic illness, specifically those with Sickle Cell Disease (SCD) or brain tumors. In addition, King currently directs the Heartland and Southwest Sickle Cell Disease Network, a partnership with SCD care providers and community organizations to improve overall care and quality of life in patients with SCD in an eight-state region that includes Missouri, Iowa, Kansas, Nebraska, Arkansas, Louisiana, Texas and Oklahoma.
Current research projects include:
- Environmental impact on children with chronic illness
- Studying the relationship between maternal mental health and child development among children with SCD
- Development and/or validation of assessments of participation and quality of life of infants and toddlers 0-48 months old
- Development and implementation of a transition program for adolescents with SCD
- Qualitative analysis of focus group sessions to better understand the needs of patients with SCD
- Assessing the effects of SCD on cognition, functional task performance, and health literacy in adolescents and adults
- Dissemination and implementation of standardized cognitive assessments for adolescents and young adults with SCD
- Investigating the consequences of hearing loss on cognitive late effects in brain tumor survivors
Student activities
Students are expected to complete at least one hypothesis-driven project focusing on either children or adults with SCD or children with brain tumors. Projects could be a retrospective study or a cross-sectional, prospective study. The results will focus on educational and functional outcomes. OTD students may publish a manuscript by the end of the final year. Most of the research will be completed at St. Louis Children’s Hospital or at the Program in Occupational Therapy building. Students may occasionally need to drive if their project involves home interviews or community education programs. Some studies may involve evening or weekend research.
Project examples
- Evaluate the effects of home environment and parental stress on developmental outcomes of children with SCD
- Develop relationships with community associations to address educational attainment for children with chronic diseases
- Assess effectiveness of an educational video about SCD
- Educate adolescents with chronic illnesses to improve independent living skills and facilitate transition from pediatric to adult health care and independent living
- Validate an activity card sort for infants and toddlers, 0-48 months old
- Assess cognition, functional task performance, and health literacy in adolescents and adults with SCD utilizing the National Institutes of Health (NIH) Toolbox, Weschler Abbreviated Scales of Intelligence (WASI-II), Executive Function Performance Test (EFPT) and Weekly Calendar Planning Activity (WCPA)
- Qualitative analysis of focus group interviews with patients and families dealing with SCD
Allison King, MD, MPH, PhD
Professor of Pediatrics, Hematology & Oncology
Researcher, Patient Oriented Research Unit
Professor, Education
Professor, Hematology
Professor, Occupational Therapy
Professor, Surgery
Director, Sickle Cell Disease Transition Program
Recent publications
- A multilevel mHealth intervention boosts adherence to hydroxyurea in individuals with sickle cell diseaseSickle Cell Disease Implementation Consortium, King, A., Baumann Walker, A. A. & Klesges, L. M., Dec 12 2023, In: Blood Advances. 7, 23, p. 7190-7201 12 p.Research output: Contribution to journal › Article › peer-review
- Symptom management care pathway adaptation process and specific adaptation decisionsVettese, E., Sherani, F., King, A. A., Yu, L., Aftandilian, C., Baggott, C., Agarwal, V., Nagasubramanian, R., Kelly, K. M., Freyer, D. R., Orgel, E., Bradfield, S. M., Kyono, W., Roth, M., Klesges, L. M., Beauchemin, M., Grimes, A., Tomlinson, G., Dupuis, L. L. & Sung, L., Dec 2023, In: BMC Cancer. 23, 1, 350.Research output: Contribution to journal › Article › peer-review
- Return visit rates after an emergency department discharge for children with sickle cell pain episodesColeman, K. D., McKinley, K., Ellison, A. M., Alpern, E. R., Hariharan, S., Topoz, I., Wurtz, M., Nielsen, B., Cook, L. J., Morris, C. R., Brandow, A. M., Campbell, A. D., Liem, R. I., Nuss, R., Quinn, C. T., Thompson, A. A., Villella, A., King, A. A., Baumann, A., Frankenberger, W., & 1 othersBrousseau, D. C., Oct 2023, In: Pediatric Blood and Cancer. 70, 10, e30553.Research output: Contribution to journal › Article › peer-review
- Clinical practice guideline and expert consensus recommendations for rehabilitation among children with cancer: A systematic reviewL’Hotta, A. J., Randolph, S. B., Reader, B., Lipsey, K. & King, A. A., Sep 1 2023, In: CA Cancer Journal for Clinicians. 73, 5, p. 524-545 22 p.Research output: Contribution to journal › Review article › peer-review
- Burden of Aging: Health Outcomes Among Adolescents and Young Adults With Sickle Cell DiseaseHowell, K. E., Pugh, N., Longoria, J., Shah, N., Kutlar, A., Gordeuk, V. R., King, A. A., Glassberg, J., Kayle, M., Melvin, C., Treadwell, M., Hankins, J. S. & Porter, J. S., Aug 13 2023, In: HemaSphere. 7, 8, e930.Research output: Contribution to journal › Letter › peer-review
- Influence of participant and reviewer characteristics in application scores for a hematology research training programVesely, S. K., King, A., Vettese, E., Heller, J. G., Cuker, A., Calhoun, C., Stock, W., Homer, M., Fritz, J. & Sung, L., Aug 8 2023, In: Blood Advances. 7, 15, p. 4064-4071 8 p.Research output: Contribution to journal › Article › peer-review
- Eye-related quality of life and activities of daily living in pediatric retinoblastoma patients: A single-center, non-controlled, cross-sectional analysisWise, J., Hayashi, R., Wu, T., Malone, S., Badawi, A. A., King, A., Gordon, M., Kimera, L., Lueder, G. & Reynolds, M., Aug 2023, In: Pediatric Blood and Cancer. 70, 8, e30479.Research output: Contribution to journal › Article › peer-review
- Defining global strategies to improve outcomes in sickle cell disease: a Lancet Haematology CommissionPiel, F. B., Rees, D. C., DeBaun, M. R., Nnodu, O., Ranque, B., Thompson, A. A., Ware, R. E., Abboud, M. R., Abraham, A., Ambrose, E. E., Andemariam, B., Colah, R., Colombatti, R., Conran, N., Costa, F. F., Cronin, R. M., de Montalembert, M., Elion, J., Esrick, E., Greenway, A. L., & 13 othersIdris, I. M., Issom, D. Z., Jain, D., Jordan, L. C., Kaplan, Z. S., King, A. A., Lloyd-Puryear, M., Oppong, S. A., Sharma, A., Sung, L., Tshilolo, L., Wilkie, D. J. & Ohene-Frempong, K., […]
- Cognition and education benefits of increased hemoglobin and blood oxygenation in children with sickle cell diseaseMacEwan, J. P., King, A. A., Nguyen, A., Mubayi, A., Agodoa, I. & Smith-Whitley, K., Aug 2023, In: PloS one. 18, 8 August, e0289642.Research output: Contribution to journal › Article › peer-review
- Characterization of vision in pediatric retinoblastoma survivors beyond visual acuityReynolds, M., Wise, J., Wu, T., Malone, S., Al Badawi, A., King, A., Gordon, M., Lueder, G. & Hayashi, R., Aug 2023, In: Journal of AAPOS. 27, 4, p. 188.e1-188.e6Research output: Contribution to journal › Article › peer-review