Active Research Grants

Parul Bakhshi, PhD, DEA (MPhil)

Title: Teachers adaptation to the SARS-cov2 outbreak in rural Afghanistan and Pakistan
Principal Investigator: Jean-Francois Trani, PhD, MA
Co-Investigators: Parul Bakhshi, PhD, DEA (MPhil), and Farah Said, MSc
Funding Source: Institute of Public Health, Center for Dissemination and Implementation, Rapid D&I Add-on Funding (RAD), Washington University in St Louis
Project Period: 7/20-9/20
Total Award: $15,000
Project Goals: Currently, investigators from the Brown School and the Program in Occupational Therapy are investigating inclusion in the learning process of primary school children implementing a randomized control field experiment in 210 intervention and control schools of three provinces of Afghanistan and two provinces of Pakistan. With the RAD add-on funding , with local non-governmental organizations partners, the investigators are implementing a large-scale telephone survey interviewing more than 400 teachers from the schools about the consequences of the current SARS-cov-2 outbreak with three aims measuring (i) prevalence level of dropout and of child labor, (ii) the disruption of the learning process, (iii) teachers’, children’s and parents’ physical and mental wellbeing.


Peggy Barco, OTD, BSW, OTR/L, SCDCM, CDRS

Title: Rural Driving and Traffic Signs
Principal Investigator:
Peggy Barco, OTD, BSW, OTR/L, SCDCM. CDRS
Funding Source: MODOT
Project Period: 10/1/18-9/30/19
Total Award: $150,000

Title: At-risk Driving and Compensatory Strategies in Older Adults with Glaucoma
Principal Investigator: Anjali M. Bhorade, MD
OT Investigator: Peggy Barco, OTD, BSW, OTR/L, SCDCM, CDRS
Funding Source: US NIH/NEI 1R01ET26199
Project Period: 3/1/16-2/28/21

Title: Patient Engagement Intervention in Inpatient Spinal Cord Injury Rehabilitation
Principal Investigator: Alex Wong, PhD, DPhil, BSOT
OT Investigators: Peggy Barco, OTD, BSW, OTR/L, SCDCM, CDRS
Funding Source: 
542448 Craig H. Neilsen Foundation’s Psychosocial Research (PSR) Grants
Project Period: 10/31/18-10/30/21
Total Award: $234,941


M. Carolyn Baum, PhD, OTR, FAOTA

 Title: Schultz Lifestyle Profile Series

Principal Investigator: M. Carolyn Baum, PhD, OTR, FAOTA
Funding Source: Schultz Family Support Fund
Project Period: 5/09-present
Total Award: $354,675

Title: Multicenter Career Development Program for Physical and Occupational Therapy
Parent Grant Principal Investigator: Michael J. Mueller, PhD
Program Director/Executive Committee/Mentor: M. Carolyn Baum, PhD, OTR, FAOTA , Program in Occupational Therapy
Funding Source: K12HD055931 NIH/NICHD Multicenter Career Development Program For Physical and Occupational Therapy Comprehensive Opportunities in Rehabilitation Research Training (CORRT) Program
Project Period: 9/1/16-8/31/22


Chih-Hung Chang, PhD

Title: IMPACT-Instrument to Measure Pain and Assess Correlation to Treatment
Principal Investigator: Tony Ma, President, Benten Technologies, Inc.
OT Investigator: Chih-Hung Chang, PhD
Funding Source: NIH/NIDA (SBIR) R43DA046974
Project Period: 9/30/19-8/31/21
Total Award: $338,947
Project Goals: This Small Business Innovation Research (SBIR) phase I project proposes the development of a prototype mobile device, to help clinicians record reliable biomarkers and surrogate markers of pain and opioid efficacy.


Erin Foster, PhD, OTD, OTR/L

Title: Early Predictors of Brain Health and Development in Youth with T1DM (NEWT)
Principal Investigator: Tamara Hershey, PhD
OT Investigator: Erin Foster, PhD, OTR/L
Funding Source: US NIH/NIDDK 2R01DK064832-11
Project Period: 5/1/16-4/30/21
Total Award: $432,616

Title: Strategy-based cognitive intervention for Parkinson disease: A pilot randomized
controlled trial
Principal Investigator: Erin Foster, PhD, OTD, OTR/L
Funding Source: NIH/NIA R21AG063974
Project Period: 8/15/19-4/30/21
Total Award: $439,552

Project Title: Prospective memory impairment in Parkinson disease-related cognitive decline: Intervention and mechanisms
Principal Investigator: Erin Foster, PhD, OTD, OTR/L
Funding Source: NIH/NIA R01AG065214
Project Period: 09/15/2020-05/31/2025
Total Award: $2,378,444
Project Goals: The long term goal of this research is to reduce disability, improve quality of life, and delay dementia onset among people with Parkinson disease (PD) by enabling them to cope with cognitive decline to maintain daily function. The primary objective of the current project is to determine the efficacy of a mechanistically-targeted strategy training intervention on prospective memory among people with PD-related mild cognitive impairment (PDMCI). It is a single-blind randomized controlled trial comparing the effects of strategy training to the traditional process training approach on objective laboratory prospective memory performance (Aim 1) and reported everyday prospective memory function (Aim 2). Additional objectives of the current project are to investigate neural mechanisms of prospective memory impairment in PD (Aim 3) and neural and behavioral predictors of prospective memory training response (Aim 4). This project leverages participants, data and infrastructure from an existing longitudinal cohort of PD and control participants to evaluate short-term and long-term training effects, neurobiological mechanisms, and predictors of treatment response.


Kelly Harris, PhD, CCC-SLP

Title: Barriers and Facilitators to Implementing Academic Supports in Pediatric Asthma
OT Investigator: Kelly Harris, PhD, CCC-SLP, Clinical Research Scholar
Principal Investigator: Victoria Frasier, MD (WU)
Funding Source: NIH National Center for Advancing Translational Sciences (NCATS) WU Institute of Clinical and Translational Sciences (ICTS) KL2TR002346 Career Development Award
Project Period: 03/01/2020-02/28/2022
Total Award: $200,000
Project Goals: Through a research-school partnership, the aims of this KL2 proposal seek to: 1) assess the reach and effectiveness of medicaland academic supports for youth with asthma in partner school districts using existing data, and 2) conduct a formative assessment to identify barriers and facilitators, existing processes, and implementation strategies influencing the implementation of these supports in partner school districts.

Title: A Research - School Partnership to Assess Barriers and Facilitators of School- Based Chronic Disease Management
OT Investigator: Kelly Harris, PhD, CCC-SLP
Principal Investigator: Betty Pace, MD (Augusta University)
Funding Source: NIH/NHLBI 2R25HL106365-10 Programs to Increase Diversity Among Individuals Engaged (Pride) in Health-Related Research, Functional & Translational Genomics of Blood Disorders, Small Research Project
Project Period: 11/15/19-8/31/21
Total Award: $13,880
Project Goals: The overall objective of this project is to conduct a formative assessment to determine barriers and facilitators to coordinated chronic disease management (CCDM) to inform the development of an intervention to provide medical and academic supports for youth with chronic diseases in K-12 schools, our long term goal. Aim 1: Establish a collaborative interdisciplinary stakeholder team and establish a framework to conduct a formative assessment of barriers and facilitators to coordinated chronic disease management (CCDM) in K-12 schools.

 

Allison King, MD, PhD

Project Title: Sickle Cell Treatment Demonstration Program: Heartland/Southwest Sickle Cell Disease Network
Principal Investigator: Allison King, MD, PhD
Funding Source: DHHS Health Resources and Services Administration (HRSA) U1EMC27865
Project Period: 09/01/2021-08/31/2026
Total Award: $4,500,000
Project Goals: The Heartland|Southwest Sickle Cell Disease (SCD) Network, an established regional collaborative with representatives in Missouri (MO), Kansas (KS), Iowa (IA), Nebraska (NE), Arkansas (AR), Louisiana (LA), Oklahoma (OK) and Texas (TX), is uniquely suited and well-equipped to accomplish the SCD Treatment Demonstration Program’s (TDP) purpose of increasing access to quality, coordinated, comprehensive care for individuals with SCD by 1) increasing the number of clinicians and health professionals knowledgeable about the care of SCD, 2) improving the quality of care provided, and 3) improving care coordination. For over 10 years, Washington University School of Medicine (WUSM) has led the regional collaborative to improve and expand patient and provider education, community awareness of SCD, quality improvement (QI) initiatives to increase the use of evidence-based guidelines, expansion of telemedicine and telementoring, and data collection for QI and intervention. We are committed to expanding these efforts, in collaboration with fellow TDP and Newborn Screening (NBS) Follow-up Program awardees, and the Hemoglobinopathies National Coordinating Center (NCC), to improve healthcare access and overall well-being of children and adults with SCD.

Title: A Phase I Trial of Familial Haploidentical Nonmyeloablative Bone Marrow Transplantation in Children
Principal Investigator: Shalini Shenoy, MD, at the Medical College of Wisconsin (MCW)
OT Investigator: Allison King, MD, PhD
Funding Source: Children’s Discovery Institute (CDI)
Project Period: 2/1/16-1/31/21
Total Direct Cost Award: $90,133

Title: The Implementation of Cognitive Screening and Educational Support to Improve Outcomes of Adolescents and Young Adults with Sickle Cell Disease: From Clinic to the Community and Back
Principal Investigator: Allison King, MD, PhD
Funding Source: 5U01HL133994 NIH - National Heart, Lung, and Blood Institute (NHLBI)
Project Period: 8/5/16-6/30/22
Total Award: $4,321,826 over six years ($685,234 in year one)

Title: Engaging Parents of Children with Sickle Cell Anemia and their Providers in Shared-Decision Making for Hydroxyurea
Principal Investigator: Lori Crosby, PsyD (Children’s Hospital Medical Center, Cincinnati, OH)
OT Investigator: Allison King, MD, PhD
Funding Source: CDR-1609-36055 Patient-Centered Outcomes Research Institute (PCORI)
Project Period: 12/1/17-11/30/21

Title: Implementation of evidence based care for the acute treatment of sickle cell disease pain
Principal Investigator: David Brousseau, MD & Julie A. Panepinto, MD at the Medical College of Wisconsin (MCW)
OT Investigator:
Allison King, MD, PhD
Funding Source
: 1U01HL143477 NIH/NHLBI
Project Period: 9/1/18-8/31/21
Total Award: $1,085,867

Title: A Phase II Study of Cytokine Induced Memory-like (CIML) Natural Killer (NK) Cell Adoptive Therapy after Haploidentical Donor Hematopoietic Cell Transplantation
Principal Investigator: Peter Westervelt, MD, PhD
OT Investigator: Allison King, MD, PhD
Funding Source: 1UG1HL138669 NIH
Project Period: 7/27/17-6/30/24
Total Current Year Award: $170,474

Title: Impact of Hearing Impairment on Cognitive Function and Quality of Life in Pediatric Cancer Survivors
Principal Investigator: Allison King, MD, PhD
Funding Source: Children’s Discovery Institute (CDI)
Project Period: 2/1/19-1/31/22
Total Award: $450,000

Title: (SCANS) Sickle Cell Anemia Neurodevelopmental Screening - Mentoring and Research in Patient Oriented Research
Principal Investigator: Allison King, MD, PhD
Funding Source: NIH/NHLBI K24HL148305
Project Period: 9/20/19-7/31/24
Total Award: $561,321
Project Goals: The specific aims of this proposal are to: 1) determine the barriers and facilitators of surveillance and screening of early childhood development of children with sickle cell disease (SCD) age 0-3 years, and 2) identify specific implementation strategies to address the barriers and facilitators to early childhood development screening. The results will inform the appropriate intervention to improve developmental screening in children with SCD.


Kerri Morgan, PhD, OTR/L, ATP

CORRT Scholarly Project Title: Feasibility of a community-based exercise intervention for persons with spinal cord injury
CORRT Scholar Award Recipient: Kerri Morgan, PhD, OTR/L, ATP
Parent Grant, Principal Investigator: Michael J. Mueller, PhD
Funding Source: 5K12HD055931-12 NIH/NICHD Multicenter Career Development Program For Physical and Occupational Therapy Comprehensive Opportunities in Rehabilitation Research Training (CORRT) Program
Project Period: 09/1/18-08/31/21
Total Scholar Award: $405,000

Title: Wheelchair propulsion training for manual wheelchair users with SCI
Principal Investigator: Kerri Morgan, PhD, OTR/L, ATP
Funding Source: 546808 Craig H. Neilsen Foundation Spinal Cord Injury Research on the Translational Spectrum (SCIRTS)
Project Period: 7/31/18-7/30/21
Total Award: $324,000

Title: Application of the WMS for Advanced Physical Training and Endurance Testing of Manual Wheelchair Users
Principal Investigator: Joseph Klaesner, PhD
OT Investigator: Kerri Morgan, PhD, OTR/L, ATP
Funding Source: 18-02 Curators of the University of Missouri, Spinal Cord Injuries Research Program
Project Period: 7/1/18-6/30/21
Total Award: $250,000

Project Title: Adapting mHealth Technology to Improve Patient Activation & Overall Wellness for Persons with Disabilities
Principal Investigator: Kerri Morgan, PhD, OTR/L, ATP
OT Investigators: Alex Wong, PhD, DPhil, BSOT
Non-OT Investigators: Pamela Newland, RN, PhD, CMSRN, Associate Professor, Goldfarb School of Nursing Barnes Jewish College
Funding Source: Foundation for Barnes Jewish Hospital (FBJH) in conjunction with WU ICTS Clinical & Translational Research Funding Program (CTRFP) supported by the WU NCATS CTSA UL1TR002345 Award
Project Period: 03/01/2021-02/28/2022
Total Award: $58,695
Project Goals: The purpose of this study is to develop and pilot-test a fatigue self-management short message service (SMS) text intervention using mobile phones to target patient activation levels in PwD. The proposed study will: (1) develop content for a fatigue self-management intervention using SMS tailored to patient activation levels in persons with multiple sclerosis, spinal cord injury, and stroke and (2) test the feasibility and acceptability of SMS to improve patient activation for fatigue self-management in PwD. The long-term goal is to improve the health of PwD by increasing their skills, confidence, and knowledge to manage fatigue and other chronic symptoms that affect their daily life.


Benjamin Philip, PhD

Title: Quantitative Handwriting Assessment Tool for Healthy and Impaired Children
Principal Investigator: Victoria G. Swamidass, CEO, at NewVentureIQ, LLC
OT Investigator:
Benjamin Philip, PhD
Funding Source: 
1R41HD097833-01 NIH/NICHD, STTR Phase I 
Project Period: 9/26/18-8/31/21
Total Award: $240,711

Title: Effects of Motor Imagery on Functional Recovery After Nerve Injury
Principal Investigator:
Benjamin Philip, PhD
Funding Source:
American Society of Neurorehabilitation (ASNR): Clinical Research Network
Project Period:
01/01/2020-01/01/2022
Total Award:
$5,000
Project Goals:
The goal of this project is to test whether motor imagery (imagined movement) can improve functional recovery of the hand following peripheral nerve injury (PNI) in the upper limb. The specific aim of this proposal is to determine whether motor imagery can improve recovery of hand function after PNI.

Project Title: Interhemispheric Communication and Compensation in Peripheral Nerve Injury
Principal Investigator: Benjamin Philip, PhD
Funding Source: NIH NINDS R01NS114046
Project Period: 12/15/20-11/30/25
Total Award: $2,114,436
Project Goals: Our short-term goal is to identify interhemispheric mechanisms that support left hand compensation (both performance and use), and determine whether the mechanisms arise from cortical asymmetry for movement (i.e. hand dominance). This will provide the foundation for our long-term goal to develop and target therapies to improve LH compensation for patients who face challenges to rehabilitation due to chronic RH impairment. Aim 1: Identify the interhemispheric mechanisms that support LH performance after RH injury. Aim 2: Identify the interhemispheric mechanisms that support increased usage of the LH after RH injury. Aim 3: Determine whether the interhemispheric mechanism arises from cortical asymmetry.

Project Title: Interhemispheric Connectivity and Handedness in Peripheral Nerve Injury Patients
Principal Investigator: Benjamin Philip, PhD
Funding Source: Washington University Institute of Clinical & Translational Sciences
Project Period: 10/29/18-10/28/21
Total Award: $9,940
Project Goals: Just-in-time funding from Institute for Clinical & Translational Sciences and Clinical & Translational Imaging Unit to support collection of preliminary MRI data for R01 proposal on interhemispheric mechanisms underlying compensation with the non-dominant hand.


Duana Russell-Thomas, OTD, OTR/L

Title: Regional Arthritis Center (RAC) - Greater St. Louis Region
Principal Investigator: Duana Russell-Thomas, MSOT, OTR/L
Funding Source: US MO DHSS
Project Period: 7/1/20-6/30/23
Total Award: $88,998


Emily Somerville, OTD, OTR/L

Project Title: A Tailored Medication Management Intervention for Older Adults
Principal Investigator:
Emily Somerville, OTD, OTR/L
Funding Source:
American Occupational Therapy Foundation (AOTF) Intervention Research Grant (IRG) Program
Project Period:
01/01/2021-12/31/2021
Total Award:
$49,798
Project Goals: T
he current project goal is to establish the feasibility, acceptability and preliminary efficacy of TIMM to improve medication management ability with community-dwelling older adults. We will objectively test our central hypothesis by conducting a single blind, randomized controlled feasibility trial in order to: Aim 1. Determine the acceptability and feasibility of an occupational therapy intervention to improve medication adherence with community-dwelling older adults. Aim 2. Estimate the preliminary efficacy of the intervention to improve medication management ability, decrease environmental barriers and decrease inappropriate medication.

Project Title:
Addressing Mental Health in Older Adults
Principal Investigator:
Emily Somerville, OTD, OTR/L
Funding Source:
WU IPH Center for Community Health Partnership Pitch Partners2 Award, funded in conjunction with WU ICTS NCATS CTSA UL1TR002345 Award
Project Period:
03/01/2021-12/31/2021
Total Award:
$9,870
Project Goals:
Mental health problems in older adults are under-identified and under-treated. To fill this gap, we propose a complete mobile wellness clinic which includes an integrated team of professionals who provide care in the homes of older adults. The visits would consist of three main services: (1) Mental health screening, diagnosis and treatment from the psychiatrist and therapist; (2) medication review, reconciliation, and education on chronic disease management by the pharmacist; and (3) Assessment of abilities and limitations, home evaluation of function, specifically focusing on managing complex medication regimen and daily activity performance by an occupational therapist. The older adults will have 24-hour access to the team for continuity of care and support.


Susy Stark, PhD, OTR/L, FAOTA

Title: Removing Home Hazards for Older Adults Living in Affordable Housing
Principal Investigator: Susy Stark, PhD, OTR/L, FAOTA
Funding Source: US HUD MOHHU0040-17
Project Period: 12/17-11/21
Total Award: $665,000

Title: Integrating Special Populations - Hub Research Capacity, WU ICTS
Principal Investigator: Bradley Evanoff, MD, MPH
OT Investigator: Susy Stark, PhD, OTR/L, FAOTA, Director
Funding Source: US NIH/NCATS UL1TR002345-01
Project Period: 6/19/17-2/28/21
Total Award: $1,631,721

Title: Training Core, WU ICTS
Principal Investigator: Jay Piccirillo, MD, FACS
OT Investigator: Susy Stark, PhD, OTR/L, FAOTA, TL1 Associate Director
Funding Source: US NIH/NCATS TL1TR002344-01
Project Period: 6/19/17-2/28/21
Total Award: $4,830,471

Title: Retaining Participants in Longitudinal Studies of Alzheimer's Disease
OT Investigator: Susy Stark, PhD, OTR/L, FAOTA
Funding Source: National Institute on Aging via the National Alzheimer’s Coordinating Center (NACC)
Project Period: 7/1/17-6/30/21
Total Award: $299,834 

Title: COMPASS: A Novel Transition Program to Reduce Disability After Stroke
Principal Investigator: Susy Stark, PhD, OTR/L, FAOTA
Funding Source:
1R01HD092398 National Institutes of Health’s Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) and The National Center for Medical Rehabilitation Research (NCMRR)
Project Period: 8/28/17-5/31/22
Total Award: $1,354,946

Title: Building Capacity to Improve Community Participation for People Aging with Long-Term Disability Through Evidence-Based Strategies
Principal Investigator: Susy Stark, PhD, OTR/L, FAOTA
OT Investigators: Kerri Morgan, PhD, OTR/L, ATP, and Jessica Dashner, OTD, OTR/L
Funding Source: US DHHS NIDILRR 90DPCP0001
Project Period: 9/30/17-9/29/22
Total Award: $2,482,013

Title: FALLS: A Marker of Preclinical Alzheimer’s Disease
Principal Investigator: Susy Stark, PhD, OTR/L, FAOTA
Funding Source: 1R01AG057680-01A1 NIH/NIA
Project Period: 8/15/18-4/30/23
Total Scholar Award: $3,265,444

Title: Alzheimer’s Disease Research Center/ Research Education Component
Principal Investigator: John C. Morris, MD
OT Investigator: Susy Stark, PhD, OTR/L, FAOTA
Funding Source: US NIH P30AG066444
Project Period: 05/15/20-04/30/25
Project Goals: The goal of the Knight Alzheimer Disease Research Center Research Education Component is to provide a one-stop training center for comprehensive Alzheimer disease and related dementias research training for individuals along the training pipeline, including underrepresented minorities, and the development of a team of well-trained, highly effective mentors.




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